These agents can be internal or external. Some internal damaging factors include cellular damage and hormonal imbalances. External factors include environmental agents, such as UV rays Harmful elements can lead to reduced skin moisture and protection from environmental aggressors, as well as the thinning of the layers of the skin 17 , Applying CoQ10 directly to the skin can reduce the damage from internal and external agents by increasing energy production in skin cells and promoting antioxidant protection In fact, CoQ10 applied directly to the skin has been shown to reduce oxidative damage caused by UV rays and even decrease the depth of wrinkles Lastly, people with low levels of CoQ10 seems to be more likely to develop skin cancer Summary: When applied directly to the skin, CoQ10 can reduce sun damage and increase antioxidant protection.
Supplementing with CoQ10 may also help decrease the risk of skin cancer. Abnormal mitochondrial function can lead to an increased calcium uptake by the cells, the excessive production of free radicals and decreased antioxidant protection.
This can result in low energy in the brain cells and even migraines Since CoQ10 lives mainly in the mitochondria of the cells, it has been shown to improve mitochondrial function and help decrease the inflammation that may occur during migraines In fact, a study showed that supplementing with CoQ10 was three times more likely than a placebo to reduce the number of migraines in 42 people One larger study showed that 1, people with low CoQ10 levels experienced fewer and less severe headaches after treatment with CoQ10 Summary: Supplementing with CoQ10 seems to help prevent and treat migraines, as it increases mitochondrial function and reduces inflammation.
Oxidative stress can affect muscle function, and thus, exercise performance Similarly, abnormal mitochondrial function can reduce muscle energy, making it hard for muscles to contract efficiently and sustain exercise 28 , CoQ10 can help exercise performance by decreasing oxidative stress in the cells and improving mitochondrial functions In fact, one study investigated the effects of CoQ10 on physical activity.
Those supplementing with 1, mg of CoQ10 per day for 60 days showed decreased oxidative stress Moreover, supplementing with CoQ10 can help increase power during exercise and reduce fatigue, both of which can improve exercise performance 32 , 33 , Summary: Exercise performance can be affected by oxidative stress and mitochondrial dysfunction.
CoQ10 can help lower oxidative damage, promote exercise capacity and decrease fatigue. Oxidative stress can induce cell damage. This can result in metabolic diseases like diabetes Abnormal mitochondrial function has also been linked to insulin resistance CoQ10 has been shown to improve insulin sensitivity and regulate blood sugar levels Supplementing with CoQ10 might also help increase CoQ10 concentrations in the blood by up to three times in people with diabetes who typically show low levels of this compound 37 , Also, one study had people with type 2 diabetes supplement with CoQ10 for 12 weeks.
Doing so significantly reduced fasting blood sugar levels and hemoglobin A1C, which is the average of blood sugar levels over the past two to three months Lastly, CoQ10 might help prevent diabetes by stimulating the breakdown of fats and reducing the accumulation of fat cells that could lead to obesity or type 2 diabetes Summary: Supplementing with CoQ10 can help increase insulin sensitivity and improve blood sugar levels.
Oxidative stress is known to cause cell damage and affect their function If your body is unable to effectively fight oxidative damage, the structure of your cells can become damaged, possibly increasing the risk of cancer 41 , CoQ10 may protect cells from oxidative stress and promote cellular energy production, promoting their health and survival 42 , Low levels of CoQ10 have been associated with up to a Summary: CoQ10 plays a critical role in the protection of cell DNA and cell survival, both of which are strongly linked to cancer prevention and recurrence.
Mitochondrial function tends to decrease with age. Unfortunately, the brain is very susceptible to oxidative damage due to its high fatty acid content and its high demand for oxygen. This oxidative damage enhances the production of harmful compounds that could affect memory, cognition and physical functions 48 , Summary: CoQ10 has been shown to protect brain cells from oxidative damage and reduce the action of harmful compounds that can lead to brain disease.
Of all your organs, your lungs have the most contact with oxygen. This makes them very susceptible to oxidative damage. It is not intended to substitute for the medical expertise and advice of your health care provider s. We encourage you to discuss any decisions about treatment or care with your health care provider. Coenzyme Q10 NCI. Home Health Information Coenzyme Q Coenzyme Q Bottom Line. CoQ10 has not been shown to be of value in treating cancer , but it may reduce the risk of heart damage caused by one type of cancer chemotherapy drug.
The antioxidant coenzyme Q10 CoQ10 is found in most living things and is used by our cells to process energy and function properly.
Naturally occurring CoQ10 decreases as we age, and according to the National Institutes of Health , several diseases and genetic disorders are associated with, but not necessarily caused by, low levels of CoQ10, including heart disease and some cancers.
CoQ10 is available as a supplement , but whether or not the supplement improves heart function or other health outcomes is somewhat controversial. Our cells use CoQ10 to help turn the energy we consume from carbohydrates into adenosine triphosphate ATP , the form of energy our cells can actually use to carry out many critical functions in the body.
ATP is essential for healthy metabolism, bones, and neurological and muscle functioning. The body naturally produces coenzyme Q10 in quantities sufficient to prevent deficiency, and no symptoms related to CoQ10 deficiency have been observed in the general population. But amounts of the antioxidant in those foods are not high enough to significantly boost levels in the body. CoQ10 is available as a dietary supplement in several forms, including hard shell and soft gel capsules, an oral spray, and tablets.
And while there is some evidence that CoQ10 supplements may help a number of diseases, other research has yielded conflicting results.
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